Fields »
ABOUT
HELP
BLOG
FGD5

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 FGD5

Gene description

 FYVE, RhoGEF and PH domain containing 5

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Group enriched (HUVEC TERT2, TIME, U-2197)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HUVEC TERT2, TIME, U-2197)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 FGD5 (HGNC Symbol)

Synonyms

 FLJ00274, FLJ39957, ZFYVE23

Description

 FYVE, RhoGEF and PH domain containing 5 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p25.1

Chromosome location (bp)

 14818962 - 14934565

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154783 (version 83.38)

Entrez gene

 152273

UniProt

 Q6ZNL6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6ZNL6

Antibodypedia

 FGD5 antibodies

PROTEIN BROWSER
FGD5-001
FGD5-005
FGD5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FGD5-001
ENSP00000285046
ENST00000285046
Q6ZNL6 [Direct mapping]
FYVE, RhoGEF and PH domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001726 [ruffle]
GO:0005085 [guanyl-nucleotide exchange factor activity]
GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005769 [early endosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005856 [cytoskeleton]
GO:0007010 [cytoskeleton organization]
GO:0008360 [regulation of cell shape]
GO:0030027 [lamellipodium]
GO:0030036 [actin cytoskeleton organization]
GO:0031267 [small GTPase binding]
GO:0032587 [ruffle membrane]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043087 [regulation of GTPase activity]
GO:0043547 [positive regulation of GTPase activity]
GO:0046847 [filopodium assembly]
GO:0046872 [metal ion binding]
Show all
 1462 aa
159.9 kDa 		No 0
FGD5-005
ENSP00000394827
ENST00000457774
H7C0G2 [Direct mapping]
FYVE, RhoGEF and PH domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 252 aa
28.5 kDa 		No 0
FGD5-201
ENSP00000445949
ENST00000543601
B7ZM68 [Direct mapping]
FGD5 protein; FYVE, RhoGEF and PH domain-containing protein 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0046872 [metal ion binding]
Show all
 1178 aa
129.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.