Expression of SAMSN1 in cancer - Summary

CANCER ATLAS

Gene description

SAM domain, SH3 domain and nuclear localization signals 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA010645	HPA017055

GENE INFORMATION
Gene name	SAMSN1 (HGNC Symbol)
Synonyms	HACS1, NASH1, SASH2, SH3D6B, SLy2
Description	SAM domain, SH3 domain and nuclear localization signals 1 (HGNC Symbol)
Entrez gene summary	SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008]
Chromosome	21
Cytoband	q11.2
Chromosome location (bp)	14485228 - 14583402
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155307 (version 83.38)
Entrez gene	64092
UniProt	Q9NSI8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NSI8
Antibodypedia	SAMSN1 antibodies

PROTEIN BROWSER

SAMSN1-001	SAMSN1-002	SAMSN1-003	SAMSN1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SAMSN1-001 ENSP00000285670 ENST00000285670	Q9NSI8 [Direct mapping] SAM domain-containing protein SAMSN-1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0001784 [phosphotyrosine binding] GO:0002820 [negative regulation of adaptive immune response] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0044822 [poly(A) RNA binding] GO:0050732 [negative regulation of peptidyl-tyrosine phosphorylation] GO:0050869 [negative regulation of B cell activation] Show all	441 aa 49.6 kDa	No	0
SAMSN1-002 ENSP00000383411 ENST00000400566	Q9NSI8 [Direct mapping] SAM domain-containing protein SAMSN-1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0001784 [phosphotyrosine binding] GO:0002820 [negative regulation of adaptive immune response] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0044822 [poly(A) RNA binding] GO:0050732 [negative regulation of peptidyl-tyrosine phosphorylation] GO:0050869 [negative regulation of B cell activation] Show all	373 aa 41.7 kDa	No	0
SAMSN1-003 ENSP00000383409 ENST00000400564	Q9NSI8 [Direct mapping] SAM domain-containing protein SAMSN-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001726 [ruffle] GO:0001784 [phosphotyrosine binding] GO:0002820 [negative regulation of adaptive immune response] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0044822 [poly(A) RNA binding] GO:0050732 [negative regulation of peptidyl-tyrosine phosphorylation] GO:0050869 [negative regulation of B cell activation] Show all	205 aa 23.5 kDa	No	0
SAMSN1-201 ENSP00000480850 ENST00000619120	S6FRS6 [Direct mapping] SAM domain, SH3 domain and nuclear localization signals 1; SAM domain-containing protein SAMSN-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	304 aa 34.2 kDa	No	0