Expression of PPM1J in cancer - Summary

CANCER ATLAS

Gene description

Protein phosphatase, Mg2+/Mn2+ dependent, 1J

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046045

GENE INFORMATION
Gene name	PPM1J (HGNC Symbol)
Synonyms	DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ
Description	Protein phosphatase, Mg2+/Mn2+ dependent, 1J (HGNC Symbol)
Entrez gene summary	This gene encodes the serine/threonine protein phosphatase. The mouse homolog of this gene apparently belongs to the protein phosphatase 2C family of genes. The exact function of this gene is not yet known. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p13.2
Chromosome location (bp)	112709994 - 112715477
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155367 (version 83.38)
Entrez gene	333926
UniProt	Q5JR12 (UniProt - Evidence at protein level)
neXtProt	NX_Q5JR12
Antibodypedia	PPM1J antibodies

PROTEIN BROWSER

PPM1J-001	PPM1J-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPM1J-001 ENSP00000308926 ENST00000309276	Q5JR12 [Direct mapping] Protein phosphatase 1J Show all	Enzymes ENZYME proteins Hydrolases SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004722 [protein serine/threonine phosphatase activity] GO:0005515 [protein binding] GO:0006470 [protein dephosphorylation] Show all	505 aa 54.8 kDa	No	0
PPM1J-002 ENSP00000475711 ENST00000464951	Q5JR12 [Direct mapping] Protein phosphatase 1J Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] Show all	299 aa 33.5 kDa	No	0