Cell atlas - PPM1J - The Human Protein Atlas

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PPM1J

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	PPM1J
Gene description	Protein phosphatase, Mg2+/Mn2+ dependent, 1J
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Cell line enhanced (T-47d)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA046045
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA046045	HaCaT	Vesicles
	HPA046045	MCF7	Vesicles	Intensity

GENE INFORMATION
Gene name	PPM1J (HGNC Symbol)
Synonyms	DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ
Description	Protein phosphatase, Mg2+/Mn2+ dependent, 1J (HGNC Symbol)
Entrez gene summary	This gene encodes the serine/threonine protein phosphatase. The mouse homolog of this gene apparently belongs to the protein phosphatase 2C family of genes. The exact function of this gene is not yet known. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p13.2
Chromosome location (bp)	112709994 - 112715477
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155367 (version 83.38)
Entrez gene	333926
UniProt	Q5JR12 (UniProt - Evidence at protein level)
neXtProt	NX_Q5JR12
Antibodypedia	PPM1J antibodies

PROTEIN BROWSER

PPM1J-001	PPM1J-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPM1J-001 ENSP00000308926 ENST00000309276	Q5JR12 [Direct mapping] Protein phosphatase 1J Show all	Enzymes ENZYME proteins Hydrolases SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004722 [protein serine/threonine phosphatase activity] GO:0005515 [protein binding] GO:0006470 [protein dephosphorylation] Show all	505 aa 54.8 kDa	No	0
PPM1J-002 ENSP00000475711 ENST00000464951	Q5JR12 [Direct mapping] Protein phosphatase 1J Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] Show all	299 aa 33.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.