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Follicular adenocarcinomas of thyroid showed strong membranous staining. A few cases of melanomas, embryonal carcinoma of testis, duct carcinomas of breast and skin cancers displayed weak to moderate positivity. Remaining cancer cells were negative.
Cancer tissues displayed weak to moderate cytoplasmic positivity with additional membranous staining in several cases. Nuclear positivity was showed in colorectal cancers. Several cases of colorectal and breast cancers along with occasional cases of prostate, ovarian and endometrial cancers were strongly positive. Most of the cases of lymphomas, lung and renal cancers were negative.
GENE INFORMATION
Gene name
FAM126B (HGNC Symbol)
Synonyms
HYCC2, MGC39518
Description
Family with sequence similarity 126, member B (HGNC Symbol)
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)