Tissue expression of FAM126B - Summary - The Human Protein Atlas

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FAM126B

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	FAM126B
Gene description	Family with sequence similarity 126, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA036166 , HPA036167
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	FAM126B (HGNC Symbol)
Synonyms	HYCC2, MGC39518
Description	Family with sequence similarity 126, member B (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q33.1
Chromosome location (bp)	200973718 - 201071671
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155744 (version 83.38)
Entrez gene	285172
UniProt	Q8IXS8 (UniProt - Evidence at protein level)
neXtProt	NX_Q8IXS8
Antibodypedia	FAM126B antibodies

PROTEIN BROWSER

FAM126B-001	FAM126B-006	FAM126B-007	FAM126B-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM126B-001 ENSP00000393667 ENST00000418596	Q8IXS8 [Direct mapping] Protein FAM126B Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] Show all	530 aa 58.6 kDa	No	0
FAM126B-006 ENSP00000401905 ENST00000452799	C9JTA1 [Direct mapping] Protein FAM126B Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		208 aa 23.8 kDa	No	0
FAM126B-007 ENSP00000408374 ENST00000453765	C9JNS4 [Direct mapping] Protein FAM126B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		87 aa 10.3 kDa	No	0
FAM126B-008 ENSP00000412139 ENST00000446678	C9J115 [Direct mapping] Protein FAM126B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		84 aa 9.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.