Cell atlas - TMEM237 - The Human Protein Atlas

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TMEM237

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	TMEM237
Gene description	Transmembrane protein 237
Protein class	Disease related genes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TMEM237 (HGNC Symbol)
Synonyms	ALS2CR4, JBTS14
Description	Transmembrane protein 237 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a tetraspanin protein that is thought to be involved in WNT signaling. Defects in this gene are a cause of Joubert syndrome-14. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Chromosome	2
Cytoband	q33.1
Chromosome location (bp)	201620184 - 201643570
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155755 (version 83.38)
Entrez gene	65062
UniProt	Q96Q45 (UniProt - Evidence at protein level)
neXtProt	NX_Q96Q45
Antibodypedia	TMEM237 antibodies

PROTEIN BROWSER

TMEM237-001	TMEM237-002	TMEM237-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM237-001 ENSP00000386264 ENST00000409883	Q96Q45 [Direct mapping] Transmembrane protein 237 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030111 [regulation of Wnt signaling pathway] GO:0035869 [ciliary transition zone] GO:0042384 [cilium assembly] Show all	408 aa 45.5 kDa	No	4
TMEM237-002 ENSP00000387203 ENST00000409444	Q96Q45 [Direct mapping] Transmembrane protein 237 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0030111 [regulation of Wnt signaling pathway] GO:0035869 [ciliary transition zone] GO:0042384 [cilium assembly] Show all	400 aa 44.6 kDa	No	4
TMEM237-201 ENSP00000480508 ENST00000621467	A0A087WWU1 [Direct mapping] Transmembrane protein 237 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	400 aa 44.6 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.