Tissue expression of ADAMTSL3 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ADAMTSL3

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ADAMTSL3
Gene description	ADAMTS-like 3
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA034773 , HPA034774
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	ADAMTSL3 (HGNC Symbol)
Synonyms	KIAA1233, punctin-2
Description	ADAMTS-like 3 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q25.2
Chromosome location (bp)	83654086 - 84039842
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156218 (version 83.38)
Entrez gene	57188
UniProt	P82987 (UniProt - Evidence at protein level)
neXtProt	NX_P82987
Antibodypedia	ADAMTSL3 antibodies

PROTEIN BROWSER

ADAMTSL3-001	ADAMTSL3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADAMTSL3-001 ENSP00000286744 ENST00000286744	P82987 [Direct mapping] ADAMTS-like protein 3 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005578 [proteinaceous extracellular matrix] GO:0006508 [proteolysis] GO:0008233 [peptidase activity] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	1691 aa 188.7 kDa	Yes	0
ADAMTSL3-002 ENSP00000456313 ENST00000567476	P82987 [Direct mapping] ADAMTS-like protein 3 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005578 [proteinaceous extracellular matrix] GO:0006508 [proteolysis] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] Show all	1682 aa 187.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.