Expression of RAB11FIP1 in cancer - Summary

CANCER ATLAS

Gene description

RAB11 family interacting protein 1 (class I)

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA023904	HPA024010	HPA025960	CAB017037

GENE INFORMATION
Gene name	RAB11FIP1 (HGNC Symbol)
Synonyms	FLJ22524, FLJ22622, Rab11-FIP1, RCP
Description	RAB11 family interacting protein 1 (class I) (HGNC Symbol)
Entrez gene summary	This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
Chromosome	8
Cytoband	p11.23
Chromosome location (bp)	37858618 - 37899467
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156675 (version 83.38)
Entrez gene	80223
UniProt	Q6WKZ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6WKZ4
Antibodypedia	RAB11FIP1 antibodies

PROTEIN BROWSER

RAB11FIP1-001	RAB11FIP1-002	RAB11FIP1-006	RAB11FIP1-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAB11FIP1-001 ENSP00000287263 ENST00000287263	Q6WKZ4 [Direct mapping] Rab11 family-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0015031 [protein transport] GO:0017137 [Rab GTPase binding] GO:0030670 [phagocytic vesicle membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045055 [regulated secretory pathway] GO:0055037 [recycling endosome] GO:0070164 [negative regulation of adiponectin secretion] Show all	649 aa 71 kDa	No	0
RAB11FIP1-002 ENSP00000331342 ENST00000330843	Q6WKZ4 [Direct mapping] Rab11 family-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0015031 [protein transport] GO:0017137 [Rab GTPase binding] GO:0030670 [phagocytic vesicle membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045055 [regulated secretory pathway] GO:0055037 [recycling endosome] GO:0070164 [negative regulation of adiponectin secretion] Show all	1283 aa 137.2 kDa	No	0
RAB11FIP1-006 ENSP00000430680 ENST00000524118	Q6WKZ4 [Direct mapping] Rab11 family-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0015031 [protein transport] GO:0017137 [Rab GTPase binding] GO:0030670 [phagocytic vesicle membrane] GO:0043231 [intracellular membrane-bounded organelle] GO:0045055 [regulated secretory pathway] GO:0055037 [recycling endosome] GO:0070164 [negative regulation of adiponectin secretion] Show all	439 aa 47.7 kDa	No	0
RAB11FIP1-008 ENSP00000430009 ENST00000522727	E7EX40 [Direct mapping] Rab11 family-interacting protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0017137 [Rab GTPase binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0045055 [regulated secretory pathway] Show all	501 aa 54.8 kDa	No	0