Expression of SASS6 in cancer - Summary

CANCER ATLAS

Gene description

SAS-6 centriolar assembly protein

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA028187

GENE INFORMATION
Gene name	SASS6 (HGNC Symbol)
Synonyms	DKFZp761A078, FLJ22097, SAS-6, SAS6
Description	SAS-6 centriolar assembly protein (HGNC Symbol)
Entrez gene summary	SAS6 is necessary for centrosome duplication and functions during procentriole formation; SAS6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle Strnad et al., (2007) [PubMed 17681132].[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p21.2
Chromosome location (bp)	100083563 - 100132955
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000156876 (version 83.38)
Entrez gene	163786
UniProt	Q6UVJ0 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UVJ0
Antibodypedia	SASS6 antibodies

PROTEIN BROWSER

SASS6-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SASS6-001 ENSP00000287482 ENST00000287482	Q6UVJ0 [Direct mapping] Spindle assembly abnormal protein 6 homolog Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005813 [centrosome] GO:0005814 [centriole] GO:0007099 [centriole replication] GO:0051298 [centrosome duplication] GO:0098536 [deuterosome] Show all	657 aa 74.4 kDa	No	0