We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
A few lung and liver cancers showed strong cytoplasmic immunoreactivity. Cancer cells in general showed weak to moderate cytoplasmic positivity. Nuclear staining was observed in testicular cancers.
GENE INFORMATION
Gene name
FZD1 (HGNC Symbol)
Synonyms
DKFZp564G072
Description
Frizzled class receptor 1 (HGNC Symbol)
Entrez gene summary
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]