Cell atlas - GJD2 - The Human Protein Atlas

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GJD2

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GJD2
Gene description	Gap junction protein, delta 2, 36kDa
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GJD2 (HGNC Symbol)
Synonyms	CX36, GJA9
Description	Gap junction protein, delta 2, 36kDa (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]
Chromosome	15
Cytoband	q14
Chromosome location (bp)	34751032 - 34754965
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159248 (version 83.38)
Entrez gene	57369
UniProt	Q9UKL4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UKL4
Antibodypedia	GJD2 antibodies

PROTEIN BROWSER

GJD2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GJD2-001 ENSP00000290374 ENST00000290374	Q9UKL4 [Direct mapping] Gap junction delta-2 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0001508 [action potential] GO:0005243 [gap junction channel activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0005922 [connexon complex] GO:0007154 [cell communication] GO:0007267 [cell-cell signaling] GO:0007268 [synaptic transmission] GO:0007601 [visual perception] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	321 aa 36.1 kDa	No	4

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.