Cell atlas - PLA2G4D - The Human Protein Atlas

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PLA2G4D

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PLA2G4D
Gene description	Phospholipase A2, group IVD (cytosolic)
Protein class	Enzymes Predicted intracellular proteins RAS pathway related proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (RPMI-8226)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (RPMI-8226) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PLA2G4D (HGNC Symbol)
Synonyms	cPLA2delta
Description	Phospholipase A2, group IVD (cytosolic) (HGNC Symbol)
Entrez gene summary	The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009]
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	42067009 - 42094554
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159337 (version 83.38)
Entrez gene	283748
UniProt	Q86XP0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86XP0
Antibodypedia	PLA2G4D antibodies

PROTEIN BROWSER

PLA2G4D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLA2G4D-001 ENSP00000290472 ENST00000290472	Q86XP0 [Direct mapping] Cytosolic phospholipase A2 delta Show all	Enzymes ENZYME proteins Hydrolases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Show all	GO:0004620 [phospholipase activity] GO:0004623 [phospholipase A2 activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0009395 [phospholipid catabolic process] GO:0030659 [cytoplasmic vesicle membrane] GO:0036148 [phosphatidylglycerol acyl-chain remodeling] GO:0036149 [phosphatidylinositol acyl-chain remodeling] GO:0036150 [phosphatidylserine acyl-chain remodeling] GO:0036151 [phosphatidylcholine acyl-chain remodeling] GO:0036152 [phosphatidylethanolamine acyl-chain remodeling] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0046872 [metal ion binding] Show all	818 aa 92 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.