Tissue expression of PLA2G4D - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PLA2G4D
Gene description	Phospholipase A2, group IVD (cytosolic)
Protein class	Enzymes Predicted intracellular proteins RAS pathway related proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (prostate, skin)
GTEx:	Tissue enhanced (vagina, skin)
FANTOM5:	Tissue enriched (cervix, uterine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (prostate, skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (vagina, skin)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cervix, uterine)

GENE INFORMATION
Gene name	PLA2G4D (HGNC Symbol)
Synonyms	cPLA2delta
Description	Phospholipase A2, group IVD (cytosolic) (HGNC Symbol)
Entrez gene summary	The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009]
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	42067009 - 42094554
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000159337 (version 83.38)
Entrez gene	283748
UniProt	Q86XP0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86XP0
Antibodypedia	PLA2G4D antibodies

PROTEIN BROWSER

PLA2G4D-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PLA2G4D-001 ENSP00000290472 ENST00000290472	Q86XP0 [Direct mapping] Cytosolic phospholipase A2 delta Show all	Enzymes ENZYME proteins Hydrolases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Show all	GO:0004620 [phospholipase activity] GO:0004623 [phospholipase A2 activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006644 [phospholipid metabolic process] GO:0006654 [phosphatidic acid biosynthetic process] GO:0008152 [metabolic process] GO:0009395 [phospholipid catabolic process] GO:0030659 [cytoplasmic vesicle membrane] GO:0036148 [phosphatidylglycerol acyl-chain remodeling] GO:0036149 [phosphatidylinositol acyl-chain remodeling] GO:0036150 [phosphatidylserine acyl-chain remodeling] GO:0036151 [phosphatidylcholine acyl-chain remodeling] GO:0036152 [phosphatidylethanolamine acyl-chain remodeling] GO:0044281 [small molecule metabolic process] GO:0046474 [glycerophospholipid biosynthetic process] GO:0046872 [metal ion binding] Show all	818 aa 92 kDa	No	0