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CELF5

GENERAL INFORMATION

Gene name

 CELF5

Gene description

 CUGBP, Elav-like family member 5

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (cerebellum, cerebral cortex, hypothalamus, caudate, hippocampus)
FANTOM5:Group enriched (caudate, cerebellum, hippocampus, brain)

Protein evidence

 Evidence at protein level

Protein expression

 Selective expression in neuronal cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA042012 , HPA060336
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Hippocampus

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebellum, cerebral cortex, hypothalamus, caudate, hippocampus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (caudate, cerebellum, hippocampus, brain)

GENE INFORMATION

Gene name

 CELF5 (HGNC Symbol)

Synonyms

 BRUNOL5

Description

 CUGBP, Elav-like family member 5 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 3224703 - 3297076

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161082 (version 83.38)

Entrez gene

 60680

UniProt

 Q8N6W0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N6W0

Antibodypedia

 CELF5 antibodies

PROTEIN BROWSER
CELF5-001
CELF5-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CELF5-001
ENSP00000292672
ENST00000292672
Q8N6W0 [Direct mapping]
CUGBP Elav-like family member 5
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Predicted intracellular proteins
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006397 [mRNA processing]
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 485 aa
52.4 kDa 		No 0
CELF5-002
ENSP00000443498
ENST00000541430
Q8N6W0 [Direct mapping]
CUGBP Elav-like family member 5
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Predicted intracellular proteins
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0003723 [RNA binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006397 [mRNA processing]
Show all
 409 aa
44.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.