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DBF4B

CANCER ATLAS

Gene description

 DBF4 zinc finger B

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA048465

GENE INFORMATION

Gene name

 DBF4B (HGNC Symbol)

Synonyms

 ASKL1, chifb, DRF1, FLJ13087, ZDBF1B

Description

 DBF4 zinc finger B (HGNC Symbol)

Entrez gene summary

 This gene encodes a regulator of the cell division cycle 7 homolog (S. cerevisiae) protein, a serine-threonine kinase which links cell cycle regulation to genome duplication. This protein localizes to the nucleus and, in complex with the cell division cycle 7 homolog (S. cerevisiae) protein, may facilitate M phase progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]

Chromosome

 17

Cytoband

 q21.31

Chromosome location (bp)

 44708608 - 44752264

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161692 (version 83.38)

Entrez gene

 80174

UniProt

 Q8NFT6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NFT6

Antibodypedia

 DBF4B antibodies

PROTEIN BROWSER
DBF4B-001
DBF4B-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DBF4B-001
ENSP00000323663
ENST00000315005
Q8NFT6 [Direct mapping]
Protein DBF4 homolog B
Show all
   SCAMPI predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007049 [cell cycle]
GO:0008270 [zinc ion binding]
GO:0008284 [positive regulation of cell proliferation]
GO:0010571 [positive regulation of nuclear cell cycle DNA replication]
GO:0010971 [positive regulation of G2/M transition of mitotic cell cycle]
GO:0016235 [aggresome]
GO:0019901 [protein kinase binding]
GO:0030295 [protein kinase activator activity]
GO:0032147 [activation of protein kinase activity]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 615 aa
67.2 kDa 		No 0
DBF4B-003
ENSP00000377178
ENST00000393547
Q8NFT6 [Direct mapping]
Protein DBF4 homolog B
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003676 [nucleic acid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0007049 [cell cycle]
GO:0008270 [zinc ion binding]
GO:0008284 [positive regulation of cell proliferation]
GO:0010571 [positive regulation of nuclear cell cycle DNA replication]
GO:0010971 [positive regulation of G2/M transition of mitotic cell cycle]
GO:0016235 [aggresome]
GO:0019901 [protein kinase binding]
GO:0030295 [protein kinase activator activity]
GO:0032147 [activation of protein kinase activity]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 431 aa
47.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.