Fields »
ABOUT
HELP
BLOG
SLC30A7

GENERAL INFORMATION

Gene name

 SLC30A7

Gene description

 Solute carrier family 30 (zinc transporter), member 7

Protein class

 Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

 Intracellular,Membrane

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA018034
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC30A7 (HGNC Symbol)

Synonyms

 ZNT7, ZnTL2

Description

 Solute carrier family 30 (zinc transporter), member 7 (HGNC Symbol)

Entrez gene summary

 Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellular efflux of zinc (Seve et al., 2004 [PubMed 15154973]).[supplied by OMIM, Mar 2008]

Chromosome

 1

Cytoband

 p21.2

Chromosome location (bp)

 100896076 - 100981753

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000162695 (version 83.38)

Entrez gene

 148867

UniProt

 Q8NEW0 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8NEW0

Antibodypedia

 SLC30A7 antibodies

PROTEIN BROWSER
SLC30A7-001
SLC30A7-002
SLC30A7-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC30A7-001
ENSP00000359130
ENST00000370112
Q8NEW0 [Direct mapping]
Zinc transporter 7
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005385 [zinc ion transmembrane transporter activity]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0006812 [cation transport]
GO:0006829 [zinc II ion transport]
GO:0008324 [cation transmembrane transporter activity]
GO:0010043 [response to zinc ion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0031982 [vesicle]
GO:0032119 [sequestering of zinc ion]
GO:0044267 [cellular protein metabolic process]
GO:0048471 [perinuclear region of cytoplasm]
GO:0055085 [transmembrane transport]
GO:0061088 [regulation of sequestering of zinc ion]
GO:0070062 [extracellular exosome]
GO:0071577 [zinc II ion transmembrane transport]
Show all
 376 aa
41.6 kDa 		No 7
SLC30A7-002
ENSP00000350278
ENST00000357650
Q8NEW0 [Direct mapping]
Zinc transporter 7
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005385 [zinc ion transmembrane transporter activity]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0006812 [cation transport]
GO:0008324 [cation transmembrane transporter activity]
GO:0010043 [response to zinc ion]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0031982 [vesicle]
GO:0044267 [cellular protein metabolic process]
GO:0055085 [transmembrane transport]
GO:0061088 [regulation of sequestering of zinc ion]
GO:0070062 [extracellular exosome]
GO:0071577 [zinc II ion transmembrane transport]
Show all
 376 aa
41.6 kDa 		No 7
SLC30A7-003
ENSP00000359129
ENST00000370111
H0Y362 [Direct mapping]
Zinc transporter 7
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006812 [cation transport]
GO:0008324 [cation transmembrane transporter activity]
GO:0016021 [integral component of membrane]
GO:0055085 [transmembrane transport]
GO:0098655 [cation transmembrane transport]
Show all
 87 aa
9.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.