Expression of FCMR in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Fc fragment of IgM receptor

Protein class

Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA003910

GENE INFORMATION
Gene name	FCMR (HGNC Symbol)
Synonyms	FAIM3, TOSO
Description	Fc fragment of IgM receptor (HGNC Symbol)
Entrez gene summary	Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).[supplied by OMIM, Jul 2010]
Chromosome	1
Cytoband	q32.1
Chromosome location (bp)	206904386 - 206923247
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162894 (version 83.38)
Entrez gene	9214
UniProt	O60667 (UniProt - Evidence at protein level)
neXtProt	NX_O60667
Antibodypedia	FCMR antibodies

PROTEIN BROWSER

FCMR-001	FCMR-004	FCMR-005	FCMR-006	FCMR-007	FCMR-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FCMR-001 ENSP00000356058 ENST00000367091	O60667 [Direct mapping] Fas apoptotic inhibitory molecule 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0006968 [cellular defense response] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] Show all	390 aa 43.1 kDa	Yes	1
FCMR-004 ENSP00000404136 ENST00000442471	O60667 [Direct mapping] Fas apoptotic inhibitory molecule 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002376 [immune system process] GO:0005576 [extracellular region] GO:0006968 [cellular defense response] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] Show all	278 aa 31 kDa	No	1
FCMR-005 ENSP00000436316 ENST00000530505	E9PPV1 [Direct mapping] Protein FCMR Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	141 aa 15.2 kDa	No	0
FCMR-006 ENSP00000432936 ENST00000525793	E9PN59 [Direct mapping] Protein FCMR Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	151 aa 17.2 kDa	Yes	0
FCMR-007 ENSP00000437331 ENST00000529560	E9PMT7 [Direct mapping] Protein FCMR Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	147 aa 16.7 kDa	Yes	0
FCMR-010 ENSP00000485739 ENST00000628511	O60667 [Direct mapping] Fas apoptotic inhibitory molecule 3 Show all	SCAMPI predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002376 [immune system process] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0006968 [cellular defense response] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] Show all	306 aa 33.8 kDa	Yes	0