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VSNL1

GENERAL INFORMATION

Gene name

 VSNL1

Gene description

 Visinin-like 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (cerebral cortex)
GTEx:Group enriched (cerebral cortex, cerebellum, hippocampus, hypothalamus)
FANTOM5:Group enriched (brain, hippocampus, cerebellum)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (cerebral cortex, cerebellum, hippocampus, hypothalamus)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, hippocampus, cerebellum)

GENE INFORMATION

Gene name

 VSNL1 (HGNC Symbol)

Synonyms

 HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1

Description

 Visinin-like 1 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 p24.2

Chromosome location (bp)

 17539126 - 17657018

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163032 (version 83.38)

Entrez gene

 7447

UniProt

 P62760 (UniProt - Evidence at protein level)

neXtProt

 NX_P62760

Antibodypedia

 VSNL1 antibodies

PROTEIN BROWSER
VSNL1-001
VSNL1-002
VSNL1-003
VSNL1-004
VSNL1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
VSNL1-001
ENSP00000295156
ENST00000295156
P62760 [Direct mapping]
Visinin-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
Show all
 191 aa
22.1 kDa 		No 0
VSNL1-002
ENSP00000384719
ENST00000406397
P62760 [Direct mapping]
Visinin-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0016020 [membrane]
GO:0035774 [positive regulation of insulin secretion involved in cellular response to glucose stimulus]
GO:0045921 [positive regulation of exocytosis]
GO:0046676 [negative regulation of insulin secretion]
Show all
 191 aa
22.1 kDa 		No 0
VSNL1-003
ENSP00000384014
ENST00000404666
P62760 [Direct mapping]
Visinin-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
Show all
 191 aa
22.1 kDa 		No 0
VSNL1-004
ENSP00000405511
ENST00000457525
E7ER47 [Direct mapping]
Visinin-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 118 aa
13.8 kDa 		No 0
VSNL1-005
ENSP00000390124
ENST00000451533
E9PE24 [Direct mapping]
Visinin-like protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005509 [calcium ion binding]
Show all
 104 aa
12.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.