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ANKRD23

GENERAL INFORMATION

Gene name

 ANKRD23

Gene description

 Ankyrin repeat domain 23

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in myocytes and smooth muscle cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA036201
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ANKRD23 (HGNC Symbol)

Synonyms

 DARP, FLJ32449, MARP3

Description

 Ankyrin repeat domain 23 (HGNC Symbol)

Entrez gene summary

 This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q11.2

Chromosome location (bp)

 96824526 - 96857934

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163126 (version 83.38)

Entrez gene

 200539

UniProt

 Q86SG2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86SG2

Antibodypedia

 ANKRD23 antibodies

PROTEIN BROWSER
ANKRD23-001
ANKRD23-002
ANKRD23-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ANKRD23-001
ENSP00000321679
ENST00000318357
Q86SG2 [Direct mapping]
Ankyrin repeat domain-containing protein 23
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Predicted intracellular proteins
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0009612 [response to mechanical stimulus]
GO:0014704 [intercalated disc]
GO:0015629 [actin cytoskeleton]
GO:0030016 [myofibril]
GO:0031432 [titin binding]
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 305 aa
34.3 kDa 		No 0
ANKRD23-002
ENSP00000398987
ENST00000418232
Q86SG2 [Direct mapping]
Ankyrin repeat domain-containing protein 23
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0015629 [actin cytoskeleton]
GO:0031432 [titin binding]
Show all
 305 aa
34.3 kDa 		No 0
ANKRD23-003
ENSP00000333108
ENST00000331001
Q86SG2 [Direct mapping]
Ankyrin repeat domain-containing protein 23
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0015629 [actin cytoskeleton]
GO:0031432 [titin binding]
Show all
 263 aa
29.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.