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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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IGFN1
  • premium

    TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Immunoglobulin-like and fibronectin type III domain containing 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA050415

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Subset of cells in few cases of duct carcinomas of breast displayed moderate to strong cytoplasmic positivity. Remaining cancer tissues were mostly negative.

GENE INFORMATION

Gene name

IGFN1 (HGNC Symbol)

Synonyms

DKFZp434B1231, EEF1A2BP1

Description

Immunoglobulin-like and fibronectin type III domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

q32.1

Chromosome location (bp)

201190825 - 201228952

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163395 (version 83.38)

Entrez gene

91156

UniProt

Q86VF2 (UniProt - Evidence at protein level)

neXtProt

NX_Q86VF2

Antibodypedia

IGFN1 antibodies

PROTEIN BROWSER

IGFN1-001
IGFN1-201
IGFN1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGFN1-001
ENSP00000387975
ENST00000412892
H7BZ61 [Direct mapping]
Immunoglobulin-like and fibronectin type III domain-containing protein 1
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
1126 aa
119.6 kDa
No 0
IGFN1-201
ENSP00000295591
ENST00000295591
Q86VF2 [Direct mapping]
Immunoglobulin-like and fibronectin type III domain-containing protein 1
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0008150 [biological_process]
GO:0030018 [Z disc]
Show all
1251 aa
137.8 kDa
No 0
IGFN1-202
ENSP00000334714
ENST00000335211
Q86VF2 [Direct mapping]
Immunoglobulin-like and fibronectin type III domain-containing protein 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0008150 [biological_process]
GO:0030018 [Z disc]
Show all
3708 aa
383.8 kDa
No 0

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