Fields »
ABOUT
HELP
BLOG
RNF25

CANCER ATLAS

Gene description

 Ring finger protein 25

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036420
HPA036421

GENE INFORMATION

Gene name

 RNF25 (HGNC Symbol)

Synonyms

 AO7, FLJ13906

Description

 Ring finger protein 25 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 218663864 - 218672411

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163481 (version 83.38)

Entrez gene

 64320

UniProt

 Q96BH1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96BH1

Antibodypedia

 RNF25 antibodies

PROTEIN BROWSER
RNF25-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RNF25-001
ENSP00000295704
ENST00000295704
Q96BH1 [Direct mapping]
E3 ubiquitin-protein ligase RNF25
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004842 [ubiquitin-protein transferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051059 [NF-kappaB binding]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0061630 [ubiquitin protein ligase activity]
Show all
 459 aa
51.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.