Cell atlas - HDAC11 - The Human Protein Atlas

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HDAC11

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	HDAC11
Gene description	Histone deacetylase 11
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	15
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (T-47d)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	HDAC11
Synonyms
Description	Histone deacetylase 11 (HGNC Symbol)
Entrez gene summary	This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2009]
Chromosome	3
Cytoband	p25.1
Chromosome location (bp)	13479724 - 13506424
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163517 (version 83.38)
Entrez gene	79885
UniProt	Q96DB2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DB2
Antibodypedia	HDAC11 antibodies

PROTEIN BROWSER

HDAC11-001	HDAC11-002	HDAC11-004	HDAC11-005	HDAC11-007	HDAC11-008	HDAC11-009	HDAC11-010	HDAC11-012	HDAC11-013	HDAC11-014	HDAC11-015	HDAC11-017	HDAC11-020	HDAC11-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HDAC11-001 ENSP00000295757 ENST00000295757	Q96DB2 [Direct mapping] Histone deacetylase 11 A0A024R2I1 [Target identity:100%; Query identity:100%] Histone deacetylase 11, isoform CRA_i Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000118 [histone deacetylase complex] GO:0004407 [histone deacetylase activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0014003 [oligodendrocyte development] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0070062 [extracellular exosome] GO:0070932 [histone H3 deacetylation] Show all	347 aa 39.2 kDa	No	0
HDAC11-002 ENSP00000412514 ENST00000433119	Q658J9 [Direct mapping] Histone deacetylase 11; Histone deacetylase 11, isoform CRA_b; Putative uncharacterized protein DKFZp434L0312 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	236 aa 25.9 kDa	No	0
HDAC11-004 ENSP00000384706 ENST00000402259	B5MCS3 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	181 aa 20.4 kDa	No	0
HDAC11-005 ENSP00000384123 ENST00000402271	B5MCQ6 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	268 aa 30.7 kDa	No	0
HDAC11-007 ENSP00000385475 ENST00000404040	B5MCU6 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	247 aa 28.3 kDa	No	0
HDAC11-008 ENSP00000385528 ENST00000404548	B5MC52 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	146 aa 16.9 kDa	No	0
HDAC11-009 ENSP00000384019 ENST00000405025	B5MD06 [Direct mapping] Histone deacetylase 11; Histone deacetylase 11, isoform CRA_h Show all	Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	118 aa 13.4 kDa	No	0
HDAC11-010 ENSP00000385252 ENST00000405478	B5MCV5 [Direct mapping] Histone deacetylase 11 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all		204 aa 23.2 kDa	No	0
HDAC11-012 ENSP00000411792 ENST00000418189	C9J528 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all		107 aa 12.4 kDa	No	0
HDAC11-013 ENSP00000398651 ENST00000434848	C9JBI4 [Direct mapping] Histone deacetylase 11 Show all	Predicted intracellular proteins Show all		168 aa 18.7 kDa	No	0
HDAC11-014 ENSP00000402298 ENST00000416248	C9JMH0 [Direct mapping] Histone deacetylase 11 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all		92 aa 10.6 kDa	No	0
HDAC11-015 ENSP00000396122 ENST00000455904	C9JEC8 [Direct mapping] Histone deacetylase 11 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all		166 aa 18.6 kDa	No	0
HDAC11-017 ENSP00000395188 ENST00000437379	E7ETT9 [Direct mapping] Histone deacetylase 11 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	319 aa 35.7 kDa	No	0
HDAC11-020 ENSP00000429794 ENST00000522202	Q96DB2 [Direct mapping] Histone deacetylase 11 Show all	Enzymes ENZYME proteins Hydrolases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0000118 [histone deacetylase complex] GO:0004407 [histone deacetylase activity] GO:0005634 [nucleus] GO:0005886 [plasma membrane] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008134 [transcription factor binding] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0070062 [extracellular exosome] GO:0070932 [histone H3 deacetylation] Show all	296 aa 33.1 kDa	No	0
HDAC11-201 ENSP00000401487 ENST00000446613	Q658J9 [Direct mapping] Histone deacetylase 11; Histone deacetylase 11, isoform CRA_b; Putative uncharacterized protein DKFZp434L0312 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] Show all	236 aa 25.9 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.