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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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TRAT1
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

TRAT1

Gene description

T cell receptor associated transmembrane adaptor 1

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (lymph node, appendix)
GTEx:Tissue enhanced (spleen, small intestine)
FANTOM5:Group enriched (spleen, lymph node, tonsil, appendix, small intestine, lung, urinary bladder)

Protein evidence

Evidence at protein level

Protein expression

Selective cytoplasmic expression in subsets of immune cells.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 2 antibodies.
HPA002356 , CAB026130
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Tonsil

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lymph node, appendix)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen, small intestine)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (spleen, lymph node, tonsil, appendix, small intestine, lung, urinary bladder)

GENE INFORMATION

Gene name

TRAT1 (HGNC Symbol)

Synonyms

HSPC062, TCRIM, TRIM

Description

T cell receptor associated transmembrane adaptor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

3

Cytoband

q13.13

Chromosome location (bp)

108822698 - 108855005

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000163519 (version 83.38)

Entrez gene

50852

UniProt

Q6PIZ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q6PIZ9

Antibodypedia

TRAT1 antibodies

PROTEIN BROWSER

TRAT1-001
TRAT1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRAT1-001
ENSP00000295756
ENST00000295756
Q6PIZ9 [Direct mapping]
T-cell receptor-associated transmembrane adapter 1
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001920 [negative regulation of receptor recycling]
GO:0002250 [adaptive immune response]
GO:0005068 [transmembrane receptor protein tyrosine kinase adaptor activity]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006968 [cellular defense response]
GO:0007165 [signal transduction]
GO:0007173 [epidermal growth factor receptor signaling pathway]
GO:0008543 [fibroblast growth factor receptor signaling pathway]
GO:0038095 [Fc-epsilon receptor signaling pathway]
GO:0042101 [T cell receptor complex]
GO:0045087 [innate immune response]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0048015 [phosphatidylinositol-mediated signaling]
GO:0050850 [positive regulation of calcium-mediated signaling]
GO:0050852 [T cell receptor signaling pathway]
GO:0050862 [positive regulation of T cell receptor signaling pathway]
GO:0051051 [negative regulation of transport]
Show all
186 aa
21.2 kDa
No 1
TRAT1-002
ENSP00000410097
ENST00000426646
C9JF66 [Direct mapping]
T-cell receptor-associated transmembrane adapter 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
149 aa
17.1 kDa
No 0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.