Cell atlas - GYG1 - The Human Protein Atlas

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GYG1

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	GYG1
Gene description	Glycogenin 1
Protein class	Disease related genes Enzymes Potential drug targets Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA030497
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA030497	A-431	Vesicles
	HPA030497	U-2 OS	Vesicles
	HPA030497	U-251 MG	Vesicles

GENE INFORMATION
Gene name	GYG1 (HGNC Symbol)
Synonyms	GYG
Description	Glycogenin 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the glycogenin family. Glycogenin is a glycosyltransferase that catalyzes the formation of a short glucose polymer from uridine diphosphate glucose in an autoglucosylation reaction. This reaction is followed by elongation and branching of the polymer, catalyzed by glycogen synthase and branching enzyme, to form glycogen. This gene is expressed in muscle and other tissues. Mutations in this gene result in glycogen storage disease XV. This gene has pseudogenes on chromosomes 1, 8 and 13 respectively. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Chromosome	3
Cytoband	q24
Chromosome location (bp)	148991341 - 149027668
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163754 (version 83.38)
Entrez gene	2992
UniProt	P46976 (UniProt - Evidence at protein level)
neXtProt	NX_P46976
Antibodypedia	GYG1 antibodies

PROTEIN BROWSER

GYG1-001	GYG1-002	GYG1-003	GYG1-004	GYG1-007	GYG1-008	GYG1-009	GYG1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GYG1-001 ENSP00000340736 ENST00000345003	P46976 [Direct mapping] Glycogenin-1 Show all	Enzymes ENZYME proteins Transferases SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0005980 [glycogen catabolic process] GO:0006006 [glucose metabolic process] GO:0008466 [glycogenin glucosyltransferase activity] GO:0016020 [membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0043202 [lysosomal lumen] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	350 aa 39.4 kDa	No	0
GYG1-002 ENSP00000296048 ENST00000296048	P46976 [Direct mapping] Glycogenin-1 Show all	Enzymes ENZYME proteins Transferases THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0005980 [glycogen catabolic process] GO:0006006 [glucose metabolic process] GO:0008466 [glycogenin glucosyltransferase activity] GO:0016020 [membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0043202 [lysosomal lumen] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	333 aa 37.5 kDa	No	0
GYG1-003 ENSP00000419499 ENST00000483267	G5E9W8 [Direct mapping] Glycogenin 1, isoform CRA_e; Glycogenin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	193 aa 21.5 kDa	No	0
GYG1-004 ENSP00000420683 ENST00000484197	P46976 [Direct mapping] Glycogenin-1 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005975 [carbohydrate metabolic process] GO:0005978 [glycogen biosynthetic process] GO:0005980 [glycogen catabolic process] GO:0006006 [glucose metabolic process] GO:0008466 [glycogenin glucosyltransferase activity] GO:0016020 [membrane] GO:0016757 [transferase activity, transferring glycosyl groups] GO:0043202 [lysosomal lumen] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	279 aa 31.5 kDa	No	0
GYG1-007 ENSP00000418297 ENST00000492285	C9J7C7 [Direct mapping] Glycogenin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016757 [transferase activity, transferring glycosyl groups] Show all	110 aa 12.4 kDa	No	0
GYG1-008 ENSP00000420247 ENST00000461191	C9JQ42 [Direct mapping] Glycogenin-1 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	266 aa 30 kDa	No	0
GYG1-009 ENSP00000417671 ENST00000473005	C9J8R8 [Direct mapping] Glycogenin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016757 [transferase activity, transferring glycosyl groups] Show all	60 aa 6.8 kDa	No	0
GYG1-201 ENSP00000486061 ENST00000627418	G5E9W8 [Direct mapping] Glycogenin 1, isoform CRA_e; Glycogenin-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	193 aa 21.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.