Expression of STK17A in cancer - Summary

CANCER ATLAS

Gene description

Serine/threonine kinase 17a

Protein class

Enzymes, Plasma proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA037979

GENE INFORMATION
Gene name	STK17A (HGNC Symbol)
Synonyms	DRAK1
Description	Serine/threonine kinase 17a (HGNC Symbol)
Entrez gene summary	This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p13
Chromosome location (bp)	43582758 - 43626786
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164543 (version 83.38)
Entrez gene	9263
UniProt	Q9UEE5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UEE5
Antibodypedia	STK17A antibodies

PROTEIN BROWSER

STK17A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STK17A-001 ENSP00000319192 ENST00000319357	Q9UEE5 [Direct mapping] Serine/threonine-protein kinase 17A Show all	Enzymes ENZYME proteins Transferases Kinases CAMK Ser/Thr protein kinases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0006468 [protein phosphorylation] GO:0006915 [apoptotic process] GO:0035556 [intracellular signal transduction] GO:0043065 [positive regulation of apoptotic process] GO:2000271 [positive regulation of fibroblast apoptotic process] GO:2000377 [regulation of reactive oxygen species metabolic process] Show all	414 aa 46.6 kDa	No	1