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STK17A

GENERAL INFORMATION

Gene name

 STK17A

Gene description

 Serine/threonine kinase 17a

Protein class

 Enzymes
Plasma proteins
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Subcellular location is contradicted by limited external data.

Reliability score

 Uncertain based on 1 antibody.
HPA037979
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 STK17A (HGNC Symbol)

Synonyms

 DRAK1

Description

 Serine/threonine kinase 17a (HGNC Symbol)

Entrez gene summary

 This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p13

Chromosome location (bp)

 43582758 - 43626786

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164543 (version 83.38)

Entrez gene

 9263

UniProt

 Q9UEE5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UEE5

Antibodypedia

 STK17A antibodies

PROTEIN BROWSER
STK17A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
STK17A-001
ENSP00000319192
ENST00000319357
Q9UEE5 [Direct mapping]
Serine/threonine-protein kinase 17A
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Enzymes
   ENZYME proteins
   Transferases
   Kinases
   CAMK Ser/Thr protein kinases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0006468 [protein phosphorylation]
GO:0006915 [apoptotic process]
GO:0035556 [intracellular signal transduction]
GO:0043065 [positive regulation of apoptotic process]
GO:2000271 [positive regulation of fibroblast apoptotic process]
GO:2000377 [regulation of reactive oxygen species metabolic process]
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 414 aa
46.6 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.