We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
COG5
  • TISSUE

  • premium

    CELL

  • CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

COG5

Gene description

Component of oligomeric golgi complex 5

Protein class

Disease related genes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Uncertain based on 1 antibody.
HPA020300
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

COG5 (HGNC Symbol)

Synonyms

GOLTC1, GTC90

Description

Component of oligomeric golgi complex 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. The encoded protein is organized with conserved oligomeric Golgi complex components 6, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants. Mutations in this gene result in congenital disorder of glycosylation type 2I.[provided by RefSeq, Jan 2011]

Chromosome

7

Cytoband

q22.3

Chromosome location (bp)

107201555 - 107564514

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164597 (version 83.38)

Entrez gene

10466

UniProt

Q9UP83 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UP83

Antibodypedia

COG5 antibodies

PROTEIN BROWSER

COG5-001
COG5-002
COG5-003
COG5-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COG5-001
ENSP00000334703
ENST00000347053
Q9UP83 [Direct mapping]
Conserved oligomeric Golgi complex subunit 5
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0017119 [Golgi transport complex]
Show all
839 aa
92.7 kDa
No 0
COG5-002
ENSP00000377228
ENST00000393603
Q9UP83 [Direct mapping]
Conserved oligomeric Golgi complex subunit 5
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0017119 [Golgi transport complex]
Show all
823 aa
90.8 kDa
No 0
COG5-003
ENSP00000297135
ENST00000297135
Q9UP83 [Direct mapping]
Conserved oligomeric Golgi complex subunit 5
Show all
   MEMSAT3 predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0017119 [Golgi transport complex]
Show all
860 aa
94.9 kDa
No 0
COG5-010
ENSP00000476238
ENST00000605888
U3KQU7 [Direct mapping]
Conserved oligomeric Golgi complex subunit 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006891 [intra-Golgi vesicle-mediated transport]
GO:0017119 [Golgi transport complex]
Show all
179 aa
19.3 kDa
No 0

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.