Cell atlas - GPR85 - The Human Protein Atlas

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GPR85

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	GPR85
Gene description	G protein-coupled receptor 85
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (HEL)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (HEL) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	GPR85 (HGNC Symbol)
Synonyms	SREB2
Description	G protein-coupled receptor 85 (HGNC Symbol)
Entrez gene summary	Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	113078331 - 113087778
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164604 (version 83.38)
Entrez gene	54329
UniProt	P60893 (UniProt - Evidence at protein level)
neXtProt	NX_P60893
Antibodypedia	GPR85 antibodies

PROTEIN BROWSER

GPR85-001	GPR85-004	GPR85-005	GPR85-006	GPR85-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR85-001 ENSP00000297146 ENST00000297146	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-004 ENSP00000401178 ENST00000449591	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-005 ENSP00000396763 ENST00000424100	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-006 ENSP00000416722 ENST00000438062	C9JDK8 [Direct mapping] Probable G-protein-coupled receptor 85 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	71 aa 7.8 kDa	No	1
GPR85-008 ENSP00000415699 ENST00000449735	C9JBQ9 [Direct mapping] Probable G-protein-coupled receptor 85 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	121 aa 13.4 kDa	No	3

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.