Tissue expression of GPR85 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	GPR85
Gene description	G protein-coupled receptor 85
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex)
GTEx:	Tissue enhanced (caudate)
FANTOM5:	Tissue enhanced (caudate, cerebellum)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (caudate)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (caudate, cerebellum)

GENE INFORMATION
Gene name	GPR85 (HGNC Symbol)
Synonyms	SREB2
Description	G protein-coupled receptor 85 (HGNC Symbol)
Entrez gene summary	Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins (Matsumoto et al., 2000 [PubMed 10833454]).[supplied by OMIM, Aug 2008]
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	113078331 - 113087778
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164604 (version 83.38)
Entrez gene	54329
UniProt	P60893 (UniProt - Evidence at protein level)
neXtProt	NX_P60893
Antibodypedia	GPR85 antibodies

PROTEIN BROWSER

GPR85-001	GPR85-004	GPR85-005	GPR85-006	GPR85-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR85-001 ENSP00000297146 ENST00000297146	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-004 ENSP00000401178 ENST00000449591	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-005 ENSP00000396763 ENST00000424100	P60893 [Direct mapping] Probable G-protein coupled receptor 85 A4D0T8 [Target identity:100%; Query identity:100%] G protein-coupled receptor 85; cDNA, FLJ92962, Homo sapiens G protein-coupled receptor 85 (GPR85), mRNA Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	370 aa 42 kDa	No	7
GPR85-006 ENSP00000416722 ENST00000438062	C9JDK8 [Direct mapping] Probable G-protein-coupled receptor 85 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	71 aa 7.8 kDa	No	1
GPR85-008 ENSP00000415699 ENST00000449735	C9JBQ9 [Direct mapping] Probable G-protein-coupled receptor 85 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	121 aa 13.4 kDa	No	3