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NLGN4Y

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GENERAL INFORMATION

Gene name

 NLGN4Y

Gene description

 Neuroligin 4, Y-linked

Protein class

 Predicted membrane proteins
Predicted secreted proteins

Predicted localization

 Membrane,Secreted

Number of transcripts

 6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (HDLM-2, BJ hTERT+, U-138 MG, hTCEpi)

Protein evidence

 Evidence at transcript level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HDLM-2, BJ hTERT+, U-138 MG, hTCEpi)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 NLGN4Y (HGNC Symbol)

Synonyms

 KIAA0951

Description

 Neuroligin 4, Y-linked (HGNC Symbol)

Entrez gene summary

 This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]

Chromosome

 Y

Cytoband

 q11.221

Chromosome location (bp)

 14522638 - 14845650

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000165246 (version 83.38)

Entrez gene

 22829

UniProt

 Q8NFZ3 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8NFZ3

Antibodypedia

 NLGN4Y antibodies

PROTEIN BROWSER
NLGN4Y-001
NLGN4Y-002
NLGN4Y-003
NLGN4Y-005
NLGN4Y-006
NLGN4Y-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NLGN4Y-001
ENSP00000372325
ENST00000382872
Q8NFZ3 [Direct mapping]
Neuroligin-4, Y-linked
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0004872 [receptor activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0007158 [neuron cell-cell adhesion]
GO:0007612 [learning]
GO:0009986 [cell surface]
GO:0014069 [postsynaptic density]
GO:0030054 [cell junction]
GO:0035176 [social behavior]
GO:0042043 [neurexin family protein binding]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050804 [modulation of synaptic transmission]
GO:0050839 [cell adhesion molecule binding]
GO:0071625 [vocalization behavior]
GO:0097104 [postsynaptic membrane assembly]
GO:0097105 [presynaptic membrane assembly]
GO:0097110 [scaffold protein binding]
Show all
 648 aa
72.9 kDa 		No 1
NLGN4Y-002
ENSP00000348169
ENST00000355905
Q8NFZ3 [Direct mapping]
Neuroligin-4, Y-linked
A0A024R9E7 [Target identity:100%; Query identity:100%]
Neuroligin 4, Y-linked, isoform CRA_d
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0004872 [receptor activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0007158 [neuron cell-cell adhesion]
GO:0007612 [learning]
GO:0009986 [cell surface]
GO:0014069 [postsynaptic density]
GO:0030054 [cell junction]
GO:0035176 [social behavior]
GO:0042043 [neurexin family protein binding]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050804 [modulation of synaptic transmission]
GO:0050839 [cell adhesion molecule binding]
GO:0071625 [vocalization behavior]
GO:0097104 [postsynaptic membrane assembly]
GO:0097105 [presynaptic membrane assembly]
GO:0097110 [scaffold protein binding]
Show all
 816 aa
92 kDa 		Yes 1
NLGN4Y-003
ENSP00000372320
ENST00000382868
A6NMU8 [Direct mapping]
Neuroligin 4, Y-linked, isoform CRA_c; Neuroligin-4, Y-linked
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0016021 [integral component of membrane]
GO:0042043 [neurexin family protein binding]
Show all
 873 aa
98.5 kDa 		Yes 1
NLGN4Y-005
ENSP00000342535
ENST00000339174
Q8NFZ3 [Direct mapping]
Neuroligin-4, Y-linked
A0A024R9E7 [Target identity:100%; Query identity:100%]
Neuroligin 4, Y-linked, isoform CRA_d
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0004872 [receptor activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0007158 [neuron cell-cell adhesion]
GO:0007612 [learning]
GO:0009986 [cell surface]
GO:0014069 [postsynaptic density]
GO:0030054 [cell junction]
GO:0035176 [social behavior]
GO:0042043 [neurexin family protein binding]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050804 [modulation of synaptic transmission]
GO:0050839 [cell adhesion molecule binding]
GO:0071625 [vocalization behavior]
GO:0097104 [postsynaptic membrane assembly]
GO:0097105 [presynaptic membrane assembly]
GO:0097110 [scaffold protein binding]
Show all
 816 aa
92 kDa 		Yes 1
NLGN4Y-006
ENSP00000412638
ENST00000413217
H0Y7G6 [Direct mapping]
Neuroligin-4, Y-linked
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
 236 aa
26.5 kDa 		Yes 0
NLGN4Y-201
ENSP00000297967
ENST00000297967
Q8NFZ3 [Direct mapping]
Neuroligin-4, Y-linked
Show all
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0004872 [receptor activity]
GO:0005515 [protein binding]
GO:0005887 [integral component of plasma membrane]
GO:0007158 [neuron cell-cell adhesion]
GO:0007612 [learning]
GO:0009986 [cell surface]
GO:0014069 [postsynaptic density]
GO:0030054 [cell junction]
GO:0035176 [social behavior]
GO:0042043 [neurexin family protein binding]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0048488 [synaptic vesicle endocytosis]
GO:0050804 [modulation of synaptic transmission]
GO:0050839 [cell adhesion molecule binding]
GO:0071625 [vocalization behavior]
GO:0097104 [postsynaptic membrane assembly]
GO:0097105 [presynaptic membrane assembly]
GO:0097110 [scaffold protein binding]
Show all
 256 aa
28.9 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.