Tissue expression of HDX - Summary - The Human Protein Atlas

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HDX

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	HDX
Gene description	Highly divergent homeobox
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Sub cellular location is contradicted by external data.
Reliability score	Approved based on 1 antibody. HPA047189
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	HDX (HGNC Symbol)
Synonyms	CXorf43, FLJ30678
Description	Highly divergent homeobox (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	84317874 - 84502479
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165259 (version 83.38)
Entrez gene	139324
UniProt	Q7Z353 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z353
Antibodypedia	HDX antibodies

PROTEIN BROWSER

HDX-001	HDX-002	HDX-003	HDX-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HDX-001 ENSP00000423670 ENST00000506585	Q7Z353 [Direct mapping] Highly divergent homeobox Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	632 aa 70.2 kDa	No	0
HDX-002 ENSP00000362272 ENST00000373177	Q7Z353 [Direct mapping] Highly divergent homeobox Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	690 aa 77.2 kDa	No	0
HDX-003 ENSP00000297977 ENST00000297977	Q7Z353 [Direct mapping] Highly divergent homeobox Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	690 aa 77.2 kDa	No	0
HDX-005 ENSP00000387790 ENST00000449553	E2QRN0 [Direct mapping] Highly divergent homeobox Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		207 aa 22.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.