Expression of SLC39A2 in cancer - Summary

CANCER ATLAS

Gene description

Solute carrier family 39 (zinc transporter), member 2

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA030489

GENE INFORMATION
Gene name	SLC39A2 (HGNC Symbol)
Synonyms	ZIP2
Description	Solute carrier family 39 (zinc transporter), member 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	20999255 - 21001871
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165794 (version 83.38)
Entrez gene	29986
UniProt	Q9NP94 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NP94
Antibodypedia	SLC39A2 antibodies

PROTEIN BROWSER

SLC39A2-001	SLC39A2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC39A2-001 ENSP00000298681 ENST00000298681	Q9NP94 [Direct mapping] Zinc transporter ZIP2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0005385 [zinc ion transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006829 [zinc II ion transport] GO:0016020 [membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0071577 [zinc II ion transmembrane transport] Show all	309 aa 32.7 kDa	No	7
SLC39A2-002 ENSP00000452568 ENST00000554422	Q9NP94 [Direct mapping] Zinc transporter ZIP2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005385 [zinc ion transmembrane transporter activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006829 [zinc II ion transport] GO:0016020 [membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0030001 [metal ion transport] GO:0046873 [metal ion transmembrane transporter activity] GO:0055085 [transmembrane transport] GO:0071577 [zinc II ion transmembrane transport] Show all	85 aa 9.3 kDa	No	1