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SLC39A2

GENERAL INFORMATION

Gene name

 SLC39A2

Gene description

 Solute carrier family 39 (zinc transporter), member 2

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (seminal vesicle, skin, prostate, esophagus)
GTEx:Tissue enhanced (skin, esophagus, vagina)
FANTOM5:Tissue enriched (seminal vesicle)

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA030489
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (seminal vesicle, skin, prostate, esophagus)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skin, esophagus, vagina)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (seminal vesicle)

GENE INFORMATION

Gene name

 SLC39A2 (HGNC Symbol)

Synonyms

 ZIP2

Description

 Solute carrier family 39 (zinc transporter), member 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the ZIP family of metal ion transporters. The encoded protein functions as a zinc transporter. Mutations in this gene may be associated with susceptibility to carotid artery disease. Multiple transcript variants have been described. [provided by RefSeq, Mar 2010]

Chromosome

 14

Cytoband

 q11.2

Chromosome location (bp)

 20999255 - 21001871

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165794 (version 83.38)

Entrez gene

 29986

UniProt

 Q9NP94 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NP94

Antibodypedia

 SLC39A2 antibodies

PROTEIN BROWSER
SLC39A2-001
SLC39A2-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC39A2-001
ENSP00000298681
ENST00000298681
Q9NP94 [Direct mapping]
Zinc transporter ZIP2
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Show all
GO:0005385 [zinc ion transmembrane transporter activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006829 [zinc II ion transport]
GO:0016020 [membrane]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0030001 [metal ion transport]
GO:0046873 [metal ion transmembrane transporter activity]
GO:0055085 [transmembrane transport]
GO:0071577 [zinc II ion transmembrane transport]
Show all
 309 aa
32.7 kDa 		No 7
SLC39A2-002
ENSP00000452568
ENST00000554422
Q9NP94 [Direct mapping]
Zinc transporter ZIP2
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Show all
GO:0005385 [zinc ion transmembrane transporter activity]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006829 [zinc II ion transport]
GO:0016020 [membrane]
GO:0016023 [cytoplasmic membrane-bounded vesicle]
GO:0030001 [metal ion transport]
GO:0046873 [metal ion transmembrane transporter activity]
GO:0055085 [transmembrane transport]
GO:0071577 [zinc II ion transmembrane transport]
Show all
 85 aa
9.3 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.