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Fraction of cells in few cases of squamous cell carcinomas and rare urothelial cancer displayed moderate to strong nuclear and cytoplasmic immunoreactivity. Remaining cancer tissues were negative.
Moderate to strong membranous staining was observed in Thyroid cancer while head and neck cancers showed cytoplasmic and nuclear positivity. Few pancreatic, skin, urothelial, ovarian, cervical and liver cancers were weak to moderately stained. Remaining cancer tissues were negative.
Fraction of cells in few squamous cell carcinomas exhibited strong cytoplasmic and nuclear staining. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
RNASE7 (HGNC Symbol)
Synonyms
RAE1
Description
Ribonuclease, RNase A family, 7 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]