Cell atlas - ARHGEF40 - The Human Protein Atlas

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ARHGEF40

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ARHGEF40
Gene description	Rho guanine nucleotide exchange factor (GEF) 40
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ARHGEF40 (HGNC Symbol)
Synonyms	FLJ10357, solo
Description	Rho guanine nucleotide exchange factor (GEF) 40 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014]
Chromosome	14
Cytoband	q11.2
Chromosome location (bp)	21070270 - 21090240
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165801 (version 83.38)
Entrez gene	55701
UniProt	Q8TER5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TER5
Antibodypedia	ARHGEF40 antibodies

PROTEIN BROWSER

ARHGEF40-001	ARHGEF40-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGEF40-001 ENSP00000298694 ENST00000298694	Q8TER5 [Direct mapping] Rho guanine nucleotide exchange factor 40 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005089 [Rho guanyl-nucleotide exchange factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0035023 [regulation of Rho protein signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	1519 aa 164.7 kDa	No	0
ARHGEF40-004 ENSP00000451335 ENST00000555038	G3V3N2 [Direct mapping] Rho guanine nucleotide exchange factor 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		557 aa 58.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.