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ATP9B

CANCER ATLAS

Gene description

 ATPase, class II, type 9B

Protein class

 Enzymes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA029364

GENE INFORMATION

Gene name

 ATP9B (HGNC Symbol)

Synonyms

 ATPIIB

Description

 ATPase, class II, type 9B (HGNC Symbol)

Entrez gene summary

Chromosome

 18

Cytoband

 q23

Chromosome location (bp)

 79069285 - 79378283

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000166377 (version 83.38)

Entrez gene

 374868

UniProt

 O43861 (UniProt - Evidence at transcript level)

neXtProt

 NX_O43861

Antibodypedia

 ATP9B antibodies

PROTEIN BROWSER
ATP9B-001
ATP9B-004
ATP9B-006
ATP9B-011
ATP9B-012
ATP9B-021
ATP9B-022
ATP9B-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATP9B-001
ENSP00000398076
ENST00000426216
O43861 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0008152 [metabolic process]
GO:0015914 [phospholipid transport]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
GO:0046872 [metal ion binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072600 [establishment of protein localization to Golgi]
Show all
 1147 aa
129.3 kDa 		No >9
ATP9B-004
ENSP00000304500
ENST00000307671
O43861 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0008152 [metabolic process]
GO:0015914 [phospholipid transport]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
GO:0046872 [metal ion binding]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072600 [establishment of protein localization to Golgi]
Show all
 1136 aa
128.2 kDa 		No >9
ATP9B-006
ENSP00000466992
ENST00000586722
B4DJ94 [Direct mapping]
Probable phospholipid-transporting ATPase IIB; cDNA FLJ61123, highly similar to Homo sapiens ATPase, Class II, type 9B (ATP9B), mRNA
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
Show all
 188 aa
22 kDa 		No 1
ATP9B-011
ENSP00000465158
ENST00000588600
K7EJG1 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0045332 [phospholipid translocation]
Show all
 100 aa
10.6 kDa 		No 0
ATP9B-012
ENSP00000468218
ENST00000586672
K7ERE0 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
GO:0046872 [metal ion binding]
Show all
 193 aa
22.2 kDa 		No 3
ATP9B-021
ENSP00000464761
ENST00000589326
K7EII3 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
Show all
 145 aa
16.5 kDa 		No 0
ATP9B-022
ENSP00000468540
ENST00000589732
K7ES39 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
Show all
 140 aa
15.6 kDa 		No 0
ATP9B-201
ENSP00000442794
ENST00000458297
F6XUP2 [Direct mapping]
Probable phospholipid-transporting ATPase IIB
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0000287 [magnesium ion binding]
GO:0004012 [phospholipid-translocating ATPase activity]
GO:0005524 [ATP binding]
GO:0005768 [endosome]
GO:0005802 [trans-Golgi network]
GO:0005886 [plasma membrane]
GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER]
GO:0006897 [endocytosis]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0045332 [phospholipid translocation]
GO:0046872 [metal ion binding]
Show all
 471 aa
54.1 kDa 		No 4

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.