Tissue expression of ATP9B - Summary - The Human Protein Atlas

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ATP9B

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	ATP9B
Gene description	ATPase, class II, type 9B
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA029364
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	ATP9B (HGNC Symbol)
Synonyms	ATPIIB
Description	ATPase, class II, type 9B (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q23
Chromosome location (bp)	79069285 - 79378283
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166377 (version 83.38)
Entrez gene	374868
UniProt	O43861 (UniProt - Evidence at transcript level)
neXtProt	NX_O43861
Antibodypedia	ATP9B antibodies

PROTEIN BROWSER

ATP9B-001	ATP9B-004	ATP9B-006	ATP9B-011	ATP9B-012	ATP9B-021	ATP9B-022	ATP9B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ATP9B-001 ENSP00000398076 ENST00000426216	O43861 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] GO:0048471 [perinuclear region of cytoplasm] GO:0072600 [establishment of protein localization to Golgi] Show all	1147 aa 129.3 kDa	No	>9
ATP9B-004 ENSP00000304500 ENST00000307671	O43861 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Enzymes ENZYME proteins Hydrolases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0008152 [metabolic process] GO:0015914 [phospholipid transport] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] GO:0048471 [perinuclear region of cytoplasm] GO:0072600 [establishment of protein localization to Golgi] Show all	1136 aa 128.2 kDa	No	>9
ATP9B-006 ENSP00000466992 ENST00000586722	B4DJ94 [Direct mapping] Probable phospholipid-transporting ATPase IIB; cDNA FLJ61123, highly similar to Homo sapiens ATPase, Class II, type 9B (ATP9B), mRNA Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	188 aa 22 kDa	No	1
ATP9B-011 ENSP00000465158 ENST00000588600	K7EJG1 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004012 [phospholipid-translocating ATPase activity] GO:0005768 [endosome] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0045332 [phospholipid translocation] Show all	100 aa 10.6 kDa	No	0
ATP9B-012 ENSP00000468218 ENST00000586672	K7ERE0 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	193 aa 22.2 kDa	No	3
ATP9B-021 ENSP00000464761 ENST00000589326	K7EII3 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	145 aa 16.5 kDa	No	0
ATP9B-022 ENSP00000468540 ENST00000589732	K7ES39 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] Show all	140 aa 15.6 kDa	No	0
ATP9B-201 ENSP00000442794 ENST00000458297	F6XUP2 [Direct mapping] Probable phospholipid-transporting ATPase IIB Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000287 [magnesium ion binding] GO:0004012 [phospholipid-translocating ATPase activity] GO:0005524 [ATP binding] GO:0005768 [endosome] GO:0005802 [trans-Golgi network] GO:0005886 [plasma membrane] GO:0006890 [retrograde vesicle-mediated transport, Golgi to ER] GO:0006897 [endocytosis] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0045332 [phospholipid translocation] GO:0046872 [metal ion binding] Show all	471 aa 54.1 kDa	No	4

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.