Expression of ACSM1 in cancer - Summary

CANCER ATLAS

Gene description

Acyl-CoA synthetase medium-chain family member 1

Protein class

Enzymes, Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA046291

GENE INFORMATION
Gene name	ACSM1 (HGNC Symbol)
Synonyms	BUCS1, MACS1
Description	Acyl-CoA synthetase medium-chain family member 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.3
Chromosome location (bp)	20623237 - 20698890
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166743 (version 83.38)
Entrez gene	116285
UniProt	Q08AH1 (UniProt - Evidence at protein level)
neXtProt	NX_Q08AH1
Antibodypedia	ACSM1 antibodies

PROTEIN BROWSER

ACSM1-001	ACSM1-002	ACSM1-003	ACSM1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACSM1-001 ENSP00000301956 ENST00000307493	Q08AH1 [Direct mapping] Acyl-coenzyme A synthetase ACSM1, mitochondrial Show all	Enzymes ENZYME proteins Ligase Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003824 [catalytic activity] GO:0003996 [acyl-CoA ligase activity] GO:0005524 [ATP binding] GO:0005525 [GTP binding] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006633 [fatty acid biosynthetic process] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0015645 [fatty acid ligase activity] GO:0015980 [energy derivation by oxidation of organic compounds] GO:0018874 [benzoate metabolic process] GO:0019395 [fatty acid oxidation] GO:0019605 [butyrate metabolic process] GO:0042632 [cholesterol homeostasis] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0047760 [butyrate-CoA ligase activity] GO:0070062 [extracellular exosome] GO:0072562 [blood microparticle] Show all	577 aa 65.3 kDa	No	2
ACSM1-002 ENSP00000428047 ENST00000520010	Q08AH1 [Direct mapping] Acyl-coenzyme A synthetase ACSM1, mitochondrial Show all	Enzymes ENZYME proteins Ligase Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0003824 [catalytic activity] GO:0003996 [acyl-CoA ligase activity] GO:0005524 [ATP binding] GO:0005525 [GTP binding] GO:0005759 [mitochondrial matrix] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0015980 [energy derivation by oxidation of organic compounds] GO:0018874 [benzoate metabolic process] GO:0019395 [fatty acid oxidation] GO:0019605 [butyrate metabolic process] GO:0042632 [cholesterol homeostasis] GO:0044281 [small molecule metabolic process] GO:0046872 [metal ion binding] GO:0047760 [butyrate-CoA ligase activity] GO:0070062 [extracellular exosome] GO:0072562 [blood microparticle] Show all	577 aa 65.3 kDa	No	2
ACSM1-003 ENSP00000428830 ENST00000523065	E5RFK0 [Direct mapping] Acyl-coenzyme A synthetase ACSM1, mitochondrial Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] Show all	154 aa 18.1 kDa	No	1
ACSM1-006 ENSP00000428098 ENST00000524149	H0YAU5 [Direct mapping] Acyl-coenzyme A synthetase ACSM1, mitochondrial Show all	Predicted intracellular proteins Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	249 aa 28.1 kDa	No	0