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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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PLIN1
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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PLIN1

Gene description

Perilipin 1

Protein class

Disease related genes
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (adipose tissue)
GTEx:Group enriched (adipose tissue, breast)
FANTOM5:Group enriched (adipose tissue, breast)

Protein evidence

Evidence at protein level

Protein expression

Selective expression in adipocytes.

DATA RELIABILITY

Data reliability
description

Antibody staining consistent with RNA expression data.

Reliability score

Supported based on 3 antibodies.
HPA024299 , CAB033821 , CAB037333
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Breast

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (adipose tissue)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (adipose tissue, breast)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (adipose tissue, breast)

GENE INFORMATION

Gene name

PLIN1 (HGNC Symbol)

Synonyms

PLIN

Description

Perilipin 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]

Chromosome

15

Cytoband

q26.1

Chromosome location (bp)

89664365 - 89679427

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166819 (version 83.38)

Entrez gene

5346

UniProt

O60240 (UniProt - Evidence at protein level)

neXtProt

NX_O60240

Antibodypedia

PLIN1 antibodies

PROTEIN BROWSER

PLIN1-001
PLIN1-003
PLIN1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLIN1-001
ENSP00000300055
ENST00000300055
O60240 [Direct mapping]
Perilipin-1
Show all
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005783 [endoplasmic reticulum]
GO:0005811 [lipid particle]
GO:0006629 [lipid metabolic process]
GO:0008289 [lipid binding]
GO:0019433 [triglyceride catabolic process]
GO:0044281 [small molecule metabolic process]
Show all
522 aa
56 kDa
No 0
PLIN1-003
ENSP00000402167
ENST00000430628
O60240 [Direct mapping]
Perilipin-1
Show all
Predicted intracellular proteins
Plasma proteins
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005783 [endoplasmic reticulum]
GO:0005811 [lipid particle]
GO:0006629 [lipid metabolic process]
GO:0008289 [lipid binding]
GO:0019433 [triglyceride catabolic process]
GO:0044281 [small molecule metabolic process]
Show all
522 aa
56 kDa
No 0
PLIN1-005
ENSP00000453426
ENST00000560330
H0YM16 [Direct mapping]
Perilipin-1
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
73 aa
7.8 kDa
No 1

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