Tissue expression of C15orf48 - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

C15orf48

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	C15orf48
Gene description	Chromosome 15 open reading frame 48
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (rectum, colon)
GTEx:	Tissue enhanced (colon, small intestine)
FANTOM5:	Tissue enhanced (appendix, small intestine, testis)

Protein evidence

Evidence at protein level

Protein expression

Granular cytoplasmic expression in several tissues, most abundant in gastrointestinal tract.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Sub cellular location is contradicted by external data.
Reliability score	Approved based on 1 antibody. HPA012943
	SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (rectum, colon)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (appendix, small intestine, testis)

GENE INFORMATION
Gene name	C15orf48 (HGNC Symbol)
Synonyms	NMES1
Description	Chromosome 15 open reading frame 48 (HGNC Symbol)
Entrez gene summary	This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jun 2012]
Chromosome	15
Cytoband	q21.1
Chromosome location (bp)	45430529 - 45448761
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166920 (version 83.38)
Entrez gene	84419
UniProt	Q9C002 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9C002
Antibodypedia	C15orf48 antibodies

PROTEIN BROWSER

C15orf48-001	C15orf48-002	C15orf48-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C15orf48-001 ENSP00000341610 ENST00000344300	Q9C002 [Direct mapping] Normal mucosa of esophagus-specific gene 1 protein A0A024R5U4 [Target identity:100%; Query identity:100%] Chromosome 15 open reading frame 48, isoform CRA_a Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005739 [mitochondrion] Show all	83 aa 9.6 kDa	No	0
C15orf48-002 ENSP00000379887 ENST00000396650	Q9C002 [Direct mapping] Normal mucosa of esophagus-specific gene 1 protein A0A024R5U4 [Target identity:100%; Query identity:100%] Chromosome 15 open reading frame 48, isoform CRA_a Show all	Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	83 aa 9.6 kDa	No	0
C15orf48-003 ENSP00000452967 ENST00000558435	H0YKW5 [Direct mapping] Normal mucosa of esophagus-specific gene 1 protein Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	132 aa 14.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.