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Moderate, granular cytoplasmic staining was observed in most normal tissues. Placenta and glandular cells of colon, appendix, epididymis and prostate displayed strong immunoreactivity. Distinct extracellular positivity was observed in renal tubules, endometrial glands, epididymis and prostate. Cells of the CNS, squamous epithelium, cervix and lymphoid cells were mainly negative.