Expression of GNGT2 in cancer - Summary

CANCER ATLAS

Gene description

Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2

Protein class

Predicted intracellular proteins, RAS pathway related proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA043381

GENE INFORMATION
Gene name	GNGT2 (HGNC Symbol)
Synonyms	GNG9
Description	Guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 (HGNC Symbol)
Entrez gene summary	Phototransduction in rod and cone photoreceptors is regulated by groups of signaling proteins. The encoded protein is thought to play a crucial role in cone phototransduction. It belongs to the G protein gamma family and localized specifically in cones. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2010]
Chromosome	17
Cytoband	q21.32
Chromosome location (bp)	49202791 - 49210574
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167083 (version 83.38)
Entrez gene	2793
UniProt	O14610 (UniProt - Evidence at transcript level)
neXtProt	NX_O14610
Antibodypedia	GNGT2 antibodies

PROTEIN BROWSER

GNGT2-001	GNGT2-002	GNGT2-003	GNGT2-004	GNGT2-005	GNGT2-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GNGT2-001 ENSP00000300406 ENST00000300406	O14610 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0007602 [phototransduction] Show all	69 aa 7.7 kDa	No	0
GNGT2-002 ENSP00000422879 ENST00000511673	O14610 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Show all	Predicted intracellular proteins RAS pathway related proteins Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0007602 [phototransduction] Show all	69 aa 7.7 kDa	No	0
GNGT2-003 ENSP00000426022 ENST00000511277	O14610 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0007602 [phototransduction] Show all	69 aa 7.7 kDa	No	0
GNGT2-004 ENSP00000423924 ENST00000515635	O14610 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Show all	Predicted intracellular proteins RAS pathway related proteins Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0007602 [phototransduction] Show all	69 aa 7.7 kDa	No	0
GNGT2-005 ENSP00000421710 ENST00000507680	O14610 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Show all	GO:0003924 [GTPase activity] GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0007602 [phototransduction] Show all	69 aa 7.7 kDa	No	0
GNGT2-006 ENSP00000420946 ENST00000503070	D6RDH5 [Direct mapping] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Show all	GO:0004871 [signal transducer activity] GO:0005834 [heterotrimeric G-protein complex] GO:0007186 [G-protein coupled receptor signaling pathway] Show all	88 aa 10 kDa	No	0