Expression of ENGASE in cancer - Summary

CANCER ATLAS

Gene description

Endo-beta-N-acetylglucosaminidase

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA021551

GENE INFORMATION
Gene name	ENGASE (HGNC Symbol)
Synonyms	FLJ21865
Description	Endo-beta-N-acetylglucosaminidase (HGNC Symbol)
Entrez gene summary	This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	79074939 - 79088599
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167280 (version 83.38)
Entrez gene	64772
UniProt	Q8NFI3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NFI3
Antibodypedia	ENGASE antibodies

PROTEIN BROWSER

ENGASE-001	ENGASE-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ENGASE-001 ENSP00000462333 ENST00000579016	Q8NFI3 [Direct mapping] Cytosolic endo-beta-N-acetylglucosaminidase Show all	Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0008152 [metabolic process] GO:0033925 [mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity] Show all	743 aa 84 kDa	No	0
ENGASE-011 ENSP00000308158 ENST00000311595	F8W925 [Direct mapping] Cytosolic endo-beta-N-acetylglucosaminidase Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0033925 [mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity] Show all	365 aa 41.4 kDa	No	0