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ENGASE

GENERAL INFORMATION

Gene name

 ENGASE

Gene description

 Endo-beta-N-acetylglucosaminidase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression, including in subsets of immune cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Antibody staining in cells/structures not annotated, view images.

Reliability score

 Approved based on 1 antibody.
HPA021551
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ENGASE (HGNC Symbol)

Synonyms

 FLJ21865

Description

 Endo-beta-N-acetylglucosaminidase (HGNC Symbol)

Entrez gene summary

 This gene encodes a cytosolic enzyme which catalyzes the hydrolysis of peptides and proteins with mannose modifications to produce free oligosaccharides. [provided by RefSeq, Feb 2012]

Chromosome

 17

Cytoband

 q25.3

Chromosome location (bp)

 79074939 - 79088599

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167280 (version 83.38)

Entrez gene

 64772

UniProt

 Q8NFI3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NFI3

Antibodypedia

 ENGASE antibodies

PROTEIN BROWSER
ENGASE-001
ENGASE-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ENGASE-001
ENSP00000462333
ENST00000579016
Q8NFI3 [Direct mapping]
Cytosolic endo-beta-N-acetylglucosaminidase
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Enzymes
   ENZYME proteins
   Hydrolases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008152 [metabolic process]
GO:0033925 [mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity]
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 743 aa
84 kDa 		No 0
ENGASE-011
ENSP00000308158
ENST00000311595
F8W925 [Direct mapping]
Cytosolic endo-beta-N-acetylglucosaminidase
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0008152 [metabolic process]
GO:0033925 [mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity]
Show all
 365 aa
41.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.