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The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008]
Enzymes ENZYME proteins Transferases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0003824 [catalytic activity] GO:0003988 [acetyl-CoA C-acyltransferase activity] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0006631 [fatty acid metabolic process] GO:0006695 [cholesterol biosynthetic process] GO:0008152 [metabolic process] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] GO:0071456 [cellular response to hypoxia] GO:1901029 [negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway] GO:1902109 [negative regulation of mitochondrial membrane permeability involved in apoptotic process]
