Expression of JSRP1 in cancer - Summary

CANCER ATLAS

Gene description

Junctional sarcoplasmic reticulum protein 1

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

STAINING SUMMARY

HPA044741

GENE INFORMATION
Gene name	JSRP1 (HGNC Symbol)
Synonyms	FLJ32416, JP-45
Description	Junctional sarcoplasmic reticulum protein 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is involved in excitation-contraction coupling at the sarcoplasmic reticulum. The encoded protein can interact with CACNA1S, CACNB1, and calsequestrin to help regulate calcium influx and efflux in skeletal muscle. [provided by RefSeq, Jul 2012]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	2252252 - 2269759
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167476 (version 83.38)
Entrez gene	126306
UniProt	Q96MG2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96MG2
Antibodypedia	JSRP1 antibodies

PROTEIN BROWSER

JSRP1-001	JSRP1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
JSRP1-001 ENSP00000300961 ENST00000300961	Q96MG2 [Direct mapping] Junctional sarcoplasmic reticulum protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003009 [skeletal muscle contraction] GO:0005515 [protein binding] GO:0016529 [sarcoplasmic reticulum] GO:0033017 [sarcoplasmic reticulum membrane] GO:0060314 [regulation of ryanodine-sensitive calcium-release channel activity] GO:0072657 [protein localization to membrane] Show all	331 aa 36.3 kDa	No	0
JSRP1-003 ENSP00000465604 ENST00000593238	K7EKG1 [Direct mapping] Junctional sarcoplasmic reticulum protein 1 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		261 aa 27.8 kDa	Yes	0