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JSRP1

GENERAL INFORMATION

Gene name

 JSRP1

Gene description

 Junctional sarcoplasmic reticulum protein 1

Protein class

 Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (skeletal muscle)
GTEx:Tissue enriched (skeletal muscle)
FANTOM5:Tissue enriched (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in skeletal myocytes.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Supported based on 1 antibody.
HPA044741
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (skeletal muscle)

GENE INFORMATION

Gene name

 JSRP1 (HGNC Symbol)

Synonyms

 FLJ32416, JP-45

Description

 Junctional sarcoplasmic reticulum protein 1 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is involved in excitation-contraction coupling at the sarcoplasmic reticulum. The encoded protein can interact with CACNA1S, CACNB1, and calsequestrin to help regulate calcium influx and efflux in skeletal muscle. [provided by RefSeq, Jul 2012]

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 2252252 - 2269759

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167476 (version 83.38)

Entrez gene

 126306

UniProt

 Q96MG2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96MG2

Antibodypedia

 JSRP1 antibodies

PROTEIN BROWSER
JSRP1-001
JSRP1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
JSRP1-001
ENSP00000300961
ENST00000300961
Q96MG2 [Direct mapping]
Junctional sarcoplasmic reticulum protein 1
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003009 [skeletal muscle contraction]
GO:0005515 [protein binding]
GO:0016529 [sarcoplasmic reticulum]
GO:0033017 [sarcoplasmic reticulum membrane]
GO:0060314 [regulation of ryanodine-sensitive calcium-release channel activity]
GO:0072657 [protein localization to membrane]
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 331 aa
36.3 kDa 		No 0
JSRP1-003
ENSP00000465604
ENST00000593238
K7EKG1 [Direct mapping]
Junctional sarcoplasmic reticulum protein 1
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
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 261 aa
27.8 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.