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Several ovarian, pancreatic and urothelial cancers along with a few squamous cell carcinomas, seminomas, malignant melanomas and renal cancers displayed weak to moderate cytoplasmic and/or nuclear positivity. Remaining cancer cells were negative.
GENE INFORMATION
Gene name
C19orf33 (HGNC Symbol)
Synonyms
H2RSP, IMUP, IMUP-1, IMUP-2
Description
Chromosome 19 open reading frame 33 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene has been shown to be upregulated in SV40-immortalized fibroblasts as well as in endometrial carcinoma cells. The encoded protein is found primarily in the nucleus. This protein may play a role in placental development and diseases such as pre-eclampsia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
