Expression of ZNF444 in cancer - Summary

CANCER ATLAS

Gene description

Zinc finger protein 444

Protein class

Predicted intracellular proteins, Transcription factors

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA056895

GENE INFORMATION
Gene name	ZNF444 (HGNC Symbol)
Synonyms	EZF2, FLJ11137, ZSCAN17
Description	Zinc finger protein 444 (HGNC Symbol)
Entrez gene summary	This gene encodes a zinc finger protein which activates transcription of a scavenger receptor gene involved in the degradation of acetylated low density lipoprotein (Ac-LDL) (PMID: 11978792). This gene is located in a cluster of zinc finger genes on chromosome 19 at q13.4. A pseudogene of this gene is located on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Chromosome	19
Cytoband	q13.43
Chromosome location (bp)	56132599 - 56160893
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167685 (version 83.38)
Entrez gene	55311
UniProt	Q8N0Y2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N0Y2
Antibodypedia	ZNF444 antibodies

PROTEIN BROWSER

ZNF444-001	ZNF444-003	ZNF444-004	ZNF444-006	ZNF444-007	ZNF444-009	ZNF444-010	ZNF444-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF444-001 ENSP00000338860 ENST00000337080	Q8N0Y2 [Direct mapping] Zinc finger protein 444 A0A024R4S5 [Target identity:100%; Query identity:100%] Zinc finger protein 444, isoform CRA_b Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	327 aa 35.2 kDa	No	0
ZNF444-003 ENSP00000466287 ENST00000588358	K7ELZ3 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	72 aa 8.3 kDa	No	0
ZNF444-004 ENSP00000466666 ENST00000586123	K7EMV5 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	71 aa 8.2 kDa	No	0
ZNF444-006 ENSP00000468762 ENST00000591564	K7ESL2 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	77 aa 8.8 kDa	No	0
ZNF444-007 ENSP00000465466 ENST00000588203	K7EK55 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	44 aa 4.9 kDa	No	0
ZNF444-009 ENSP00000465171 ENST00000587467	K7EJH4 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	90 aa 10.3 kDa	No	0
ZNF444-010 ENSP00000465070 ENST00000593100	K7EJ91 [Direct mapping] Zinc finger protein 444 Show all	Predicted intracellular proteins Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] Show all	99 aa 11.3 kDa	No	0
ZNF444-013 ENSP00000468069 ENST00000592949	Q8N0Y2 [Direct mapping] Zinc finger protein 444 A0A024R4P4 [Target identity:100%; Query identity:100%] Zinc finger protein 444, isoform CRA_a Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	326 aa 35.1 kDa	No	0